Human papilloma virus, DNA methylation and microRNA expression in cervical cancer (Review)
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چکیده
منابع مشابه
Human papilloma virus, DNA methylation and microRNA expression in cervical cancer (Review)
Cancer is a complex disease caused by genetic and epigenetic abnormalities that affect gene expression. The progression from precursor lesions to invasive cervical cancer is influenced by persistent human papilloma virus (HPV) infection, which induces changes in the host genome and epigenome. Epigenetic alterations, such as aberrant miRNA expression and changes in DNA methylation status, favor ...
متن کاملHuman papilloma virus and cervical cancer.
From epidemiological viewpoint, it has been elucidated that cervical cancer is caused by something transmitted through sexual contact. At present, human papilloma virus, HPV, is thought to be one of the most important candidates, because 60-80% of invasive cancer as well as 30-50% of premalignant lesions of the cervix contain HPV, most of which is HPV-16 or 18. However, these HPVs are detected ...
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Background & Objective: Ovarian cancer is one of the most common cancers amongst women. The association of Human papillomavirus (HPV) and Epstein-Barr virus (EBV) with ovarian cancer is inconclusive; therefore, the aims of this study were to evaluate the frequency of HPV and EBV in malignant, ...
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Background: Stem Cell differentiation is a process composed of vast variety of factors which are controlled by a network of certain mechanisms. This study aims to determine the possible role of DNA methylation, a potent regulator of VHL, ECAD and RUNX3 genes during Erythroid differentiation driven by miR-451. Materials and Methods: To determine the methylation status of promoters and the e...
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Research in relation to the etiology of cervical cancer has made substantial progress in the last two decades both in scientific and operational terms. In many countries, HPV is the most common sexually transmitted infection (STI) and cervical cancer remains the second most common cancer among women worldwide. Although high risk HPV infection has been identified as the primary etiological agent...
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ژورنال
عنوان ژورنال: Oncology Reports
سال: 2014
ISSN: 1021-335X,1791-2431
DOI: 10.3892/or.2014.3142